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Glycirest (Metformin)

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Glycirest is an anti-diabetic medication. It works by lowering glucose production in the liver, delaying the absorption of sugar from the intestines, and increasing the body's sensitivity to insulin.

Other names for this medication:
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Also known as: Metformin


Glycirest XR is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Glycirest XR is sometimes used together with insulin or other medications, but this medicine is not for treating type 1 diabetes.


Glycirest can be taken in form of pills and extended-release pills which should be taken by mouth. It is better to take Glycirest every day at the same time with meal or without it. Usual Glycirest dosage is taken 2-3 times a day with meals. Glycirest XR (extended-release tablets) is taken once a day with evening meal. Take Glycirest and remember that its dosage depends on patient's health state. Glycirest can't be used by patients under 10 years. Glycirest XR (extended-release tablets) can't be used by patients under 17 years. It can be dangerous to stop Glycirest taking suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Glycirest are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use MetFORMIN (Eqv-Glycirest XR) if you are allergic to it, or if you have:

severe kidney disease; or metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking MetFORMIN (Eqv-Glycirest XR). Be sure your caregivers know ahead of time that you are using this medication.

Tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine); high ketone levels in your blood or urine; heart disease, congestive heart failure; liver disease; or if you also use insulin, or other oral diabetes medications.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

MetFORMIN (Eqv-Glycirest XR) may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breastfeed while using this medicine.

MetFORMIN (Eqv-Glycirest XR) should not be given to a child younger than 10 years old. Some forms of MetFORMIN (Eqv-Glycirest XR) are not approved for use by anyone younger than 18 years old.

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